Clinical Trials

Colorectal

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Locally advanced/metastatic, first line
Study number: GI 149 Amgen, Inc. 20080259
Protocol title: A Phase 3, Randomized, Double-blind, Placebo-Controlled Study of Pegfilgrastim Administered to Subjects with Locally Advanced or Metastatic Colorectal Cancer Treated with 5-fluorouracil, Oxaliplatin, Leucovorin (FOLFOX) or 5-fluorouracil, Irinotecan, Leucovorin (FOLFIRI) and Bevacizumab
Status Open

Metastatic 2nd Line
Study Number: GI 141 IMCL CP 20-0801  ImClone Systems, Inc.
Protocol title: An Open-label, Multicenter, Randomized  Phase 2 Study Evaluating the Safety and Efficacy of 5-FU/FA and Oxaliplatin (mFOLFOX6) in Combination with IMC-1121B or IMC-18F1 or Without Investigational Therapy as Second-line Therapy in Patients with Metastatic Colorectal Cancer following Disease Progression in First-line Irinotecan-based Therapy
Status: Open
Refractory 2nd Line
Study Number: GI 142 Perifosine 343  Keryx/AOI Pharmaceuticals
Protocol title: A Phase III Randomized Double-blind Study to Assess the Efficacy and Safety of Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients with Refractory Advanced Colorectal Cancer
Status: Open