Endometrial or uterine cancer can start in different parts of the uterus. Most uterine cancers start in the endometrium (the inner lining of the uterus). This is called endometrial cancer. Most endometrial cancers are adenocarcinomas (cancers that begin in cells that make mucus and other fluids). Uterine sarcoma is an uncommon form of uterine cancer that forms in the muscle and tissue that support the uterus.
Several factors are associated with an increased risk of endometrial cancer, including obesity, exposure to endogenous or exogenous estrogens, tamoxifen use and certain inherited conditions. You can reduce your risks with physical activity, taking combination oral contraceptives, and having a history of pregnancy and/or breast feeding.
Surgical removal of the uterus or hormone therapy is used to prevent endometrial cancer in women with abnormal overgrowth of the endometrium. There is no standard or routine screening test for endometrial cancer.