From OHC

September 25, 2024

Ovarian cancer is the deadliest gynecological cancer. There are many risk factors that increase a woman’s chance of developing ovarian cancer, including age, genetic mutations, family history, personal cancer history, and taking hormone replacement therapy.  However, a recent study has discovered that a common condition affecting between 5-10% of women and adolescents is linked to a higher risk of developing ovarian cancer.

Endometriosis is a condition where tissue similar to the lining of the uterus grows outside the uterus, typically near the reproductive organs in the pelvis or abdomen.  It can cause severe menstrual pain, as well as pain during intercourse, bowel movements, and/or urination.  Other symptoms include chronic pelvic pain, abdominal bloating, nausea, fatigue, depression, and anxiety.

According to the population-based cohort study published in JAMA, the more severe the endometriosis, the greater the risk of ovarian cancer.  The strongest correlation was between deep infiltrating endometriosis and endometriomas that grew specifically on the ovaries and type I ovarian cancer.

OHC gynecologic oncologist Ajit Gubbi, DO, explains why this correlation occurs, “The study suggests that endometriosis may actually be the source for endometrioid and clear cell ovarian cancer, which are two types of this deadly disease. Endometrioid ovarian cancer is the third most common form of ovarian cancer.”

There is also a suggestion that there may be a genetic mutation linked to both endometriosis and these ovarian cancer subtypes.

When asked what women with endometriosis should do, Dr. Gubbi suggests vigilance, “It’s imperative that women with endometriosis visit their healthcare provider annually and relay any new symptoms as they occur.  While there are no screenings for ovarian cancer, women who have completed childbearing or have other fertility options may choose more aggressive prevention strategies including the removal of their ovaries or a total hysterectomy.” Your healthcare provider can go through the options as well as the pros and cons of these decisions.

If you are experiencing any of the following symptoms, contact your healthcare provider:

  • Bloating
  • Urinary changes
  • Bowel changes
  • Abdominal discomfort
  • Appetite changes
  • Vaginal discharge
  • Unexplained weight loss
  • Fatigue

OHC’s gynecologic oncologists are renowned in treating ovarian cancer and other gynecologic cancers with robotic-assisted surgery.  Learn more about Dr. Gubbi and Dr. Bowling or schedule an appointment today.