Dené C. Wrenn, M.D., MS
Gynecologic Oncology
Patient Reviews Request Appointment
Dené C. Wrenn, MD, MS, FACOG, is a gynecologic oncologist whose specialties include minimally invasive surgery, risk-reducing surgery and new treatments for cancers of the female reproductive organs.
She brings research knowledge with a prior grant for research in endometrial cancer. Dr. Wrenn has experience teaching future clinicians by teaching and mentoring local resident physicians. She also served as a voluntary faculty member of obstetrics and gynecology at the Leonard M. Miller School of Medicine at the University of Miami.
Often recognized as one of Cincinnati’s Top Doctors, Dr. Wrenn is a member of the Society of Gynecologic Oncologists, American College of Obstetrics and Gynecology, The Gynecologic and Obstetrics Society and the Cincinnati Medical Association. She is the recipient of the J. Marion Sims Award from the Medical University of South Carolina for surgical excellence in minimally invasive surgery, gynecology, and gynecologic oncology and the Southeastern Fertility Stork Award from the Medical University of South Carolina for outstanding care and compassion to women seeking pregnancy.
Dr. Wrenn is also concerned about her patients’ well-being, and uses a philosophical and holistic approach to their care. “I treat the whole patient; mind, body, and soul. I have the clinical knowledge and expertise to treat the disease, and I use compassion and sympathy to treat the emotions that come with a cancer diagnosis.”
When she isn’t working, Dr. Wrenn enjoys spending time with friends and family.
Education & Training
Medical School: Tulane University School of Medicine, New Orleans, LA
Residency: Medical University of South Carolina, Charleston, SC
Fellowship: University of Miami, Jackson Memorial Hospital, Miami, FL
Additional Education: Tulane University, Master of Science, Cell and Molecular Biology
Board Certifications
American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
American Board of Obstetrics and Gynecology, Gynecologic Oncology
Patient Reviews
When I was diagnosed with uterine cancer, I was referred to Dr. Dené Wrenn. She took immediate action and scheduled me for surgery. She set up my chemotherapy and radiation treatments since I had a high grade cancer. I feel very fortunate to be in such good hands. Even my PCP said she did a very thorough surgery. I really feel confident that she got rid of the cancer. My cat scans have come back good, so far. Dr. Wrenn is very caring and compassionate. I highly recommend her and the entire OHC staff. – L.F., February 2021
Dr. Wrenn and the staff who support her have been a great care team for me for the past three years. They greet me by name and with a smile. They make me feel glad to come to her appointment. Dr. Wrenn is attentive to my care needs, she is patient, actively listens and has made herself available to family members, with my permission, to help explain my care and recommendations in person or virtually. She is concerned for my safety, her staff and her own, by strictly following protocols. I would highly recommend her to anyone! It is a blessing to have the expert care of Dr. Wrenn and her staff! – I.D., February 2021
Dr. Wrenn and her staff were so welcoming, professional, and attentive during my first visit. I left feeling like I was in excellent hands and that all of my questions had been answered. I cannot imagine a more kind and compassionate team! – A.R., January 2021
As always, my visit with Dr. Dene Wrenn was wonderful. Gracious, professional, considerate, patient, knowledgeable and all around wonderful human being. First met Dr. Wrenn in October, 2013 when I need to have a complete hysterotomy immediately. She was patient, explained in clear terms what the issue was and what needed to be done. There was no hesitation on our part to proceed with the surgery. It is reassuring to have such an intelligent, honest and fine person as Dr. Wrenn for my oncologist; and hopefully, friend. – S.A., January 2021